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High flow nasal oxygen during sedation in the cardiac catheterisation laboratory
A randomized controlled trial
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Authors
- Aaron Conway
Peter Munk Cardiac Centre, UHN & Lawrence S. Bloomberg Faculty of Nursing, University of Toronto
- Navpreet Kamboj
Lawrence S. Bloomberg Faculty of Nursing, University of Toronto
- Kristina Chang
Toronto General Hospital, UHN
- Matteo Parotto
Toronto General Hospital, UHN
Peter Munk Cardiac Centre, UHN & Lawrence S. Bloomberg Faculty of Nursing, University of Toronto
Lawrence S. Bloomberg Faculty of Nursing, University of Toronto
Toronto General Hospital, UHN
Toronto General Hospital, UHN
Screening
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CONSORT diagram
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Reasons for exclusion
Characteristics
Participant characteristics
| Characteristic | High Flow nasal oxygen, N = 641 | Face mask oxygen, N = 651 |
|---|---|---|
| Age (years) | 67 (14) | 70 (13) |
| Gender | ||
| Female | 19 (30%) | 17 (26%) |
| Male | 45 (70%) | 47 (72%) |
| Prefer not to say | 0 (0%) | 1 (1.5%) |
| Other | 0 (0%) | 0 (0%) |
| Smoking history | ||
| Never | 23 (36%) | 25 (38%) |
| Current | 7 (11%) | 7 (11%) |
| Past | 34 (53%) | 33 (51%) |
| Obstructive sleep apnea | 17 (27%) | 18 (28%) |
| Uses CPAP | 9 (14%) | 12 (18%) |
| Admission source | ||
| Ward | 17 (27%) | 18 (28%) |
| Day surgery | 45 (70%) | 44 (68%) |
| CVICU | 2 (3.1%) | 3 (4.6%) |
| CICU | 0 (0%) | 0 (0%) |
| ASA classification status | ||
| I | 0 (0%) | 0 (0%) |
| II | 0 (0%) | 0 (0%) |
| III | 21 (33%) | 16 (25%) |
| IV | 43 (67%) | 49 (75%) |
| Procedure | ||
| PPM | 11 (17%) | 17 (26%) |
| PPM generator change | 6 (9.4%) | 7 (11%) |
| PPM lead revision | 0 (0%) | 1 (1.5%) |
| ICD | 19 (30%) | 13 (20%) |
| ICD generator change | 10 (16%) | 13 (20%) |
| ICD lead revision | 2 (3.1%) | 0 (0%) |
| CRT-D | 11 (17%) | 11 (17%) |
| CRT-P | 2 (3.1%) | 2 (3.1%) |
| Wound revision | 0 (0%) | 0 (0%) |
| Other | 3 (4.7%) | 1 (1.5%) |
| Charlson Comorbidity Index | 4.46 (2.14) | 5.15 (2.51) |
| Total dose of midazolam (mg) | 1.58 (0.84) | 1.45 (0.71) |
| Total dose of propofol (mg) | 100 (126) | 88 (104) |
| Total dose of fentanyl (mcg) | 71 (28) | 76 (56) |
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Statistics presented: mean (SD); n (%)
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Oxygen use
Column {data-width = 500}
Oxygen flow rate in litres per minute for each participant
Oxygen flow rate in litres per minute as a proportion of the total time of all procedures per randomization group
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Oxygen to air ratio for each participant randomized to high flow nasal oxygen
CO2/SPO2 data
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Categories of recorded CO2 values during procedure for each participant
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Categories of recorded SPO2 values during procedure for each participant
Codebook
Insert a codebook: https://rubenarslan.github.io/codebook/